ARNTL2 anticorps (N-Term)

N° du produit ABIN1449870

Cet anticorps anti-ARNTL2 Polyclonal Lapin (ABIN1449870) détecte spécifiquement ARNTL2 dans WB et IHC (p). L’anticorps est réactif avec des échantillons de Humain et Poulet.

Aperçu rapide pour ARNTL2 anticorps (N-Term) (ABIN1449870)

Antigène: ARNTL2 (Aryl Hydrocarbon Receptor Nuclear Translocator-Like 2 (ARNTL2))

Reactivité: Humain, Poulet

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ARNTL2 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit anti-ARNTL2 anticorps

Épitope: N-Term

Séquence: PTAMGSFSSH MTEFPRKRKG SDSDPSQSGI MTEKVVEKLS QNPLTYLLST

Réactivité croisée (Details): Species reactivity (expected):ChickenSpecies reactivity (tested):Human.

Purification: Purified using peptide immunoaffinity column

Immunogène: Synthetic peptide directed towards the N terminal of human ARNTL2

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Reconstitution: Add 50 μL of distilled water to a final concentration of 1 mg/mL.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store lyophilized at 2-8 °C for one month or at -20 °C long term. After reconstitution store the antibody undiluted at 2-8 °C for up to one month or in aliquots at -20 °C long term.

Détails sur ARNTL2

Antigène: ARNTL2 (Aryl Hydrocarbon Receptor Nuclear Translocator-Like 2 (ARNTL2))

Autre désignation: ARNTL2 / BMAL2

Sujet: ARNTL2-CLOCK heterodimers activate E-box element (3'-CACGTG-5') transcription. Also, in umbilical vein endothelial cells, ARNTL2 activates SERPINE1 through E-box sites. This transactivation is inhibited by PER2 and CRY1. It is xxpressed in fetal brain and highly expressed in brain and placenta. Lower levels are found in heart, liver, thymus, kidney and lung. It is located to endothelial cells and neuronal cells of the suprachiasmatic nucleus (SCN) and also detected in endothelial cells of the heart, lung and kidney. In the brain, it is specifically expressed in the thalamus, hippocampus and amygdala.Synonyms: Aryl hydrocarbon receptor nuclear translocator-like protein 2, BHLHE6, Basic-helix-loop-helix-PAS protein MOP9, Brain and muscle ARNT-like 2, CLIF, CYCLE-like factor, Class E basic helix-loop-helix protein 6, MOP9, Member of PAS protein 9, PAS domain-containing protein 9, PASD9, bHLHe6

ID gène: 56938

NCBI Accession: NP_064568

Pathways: Photoperiodism