IKZF4 anticorps (N-Term)

N° du produit ABIN1449872

Détail du produit anti-IKZF4 anticorps

Antigène: IKZF4 (IKAROS Family Zinc Finger 4 (Eos) (IKZF4))

Épitope: N-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp IKZF4 est non-conjugé

Application: Western Blotting (WB)

Séquence: GSHRQGKDNL ERDPSGGCVP DFLPQAQDSN HFIMESLFCE SSGDSSLEKE

Réactivité croisée (Details): Species reactivity (expected):DogSpecies reactivity (tested):Human

Purification: Purified using peptide immunoaffinity column

Immunogène: A synthetic peptide directed towards the N-terminal region of human IKZF4

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Reconstitution: Add 50 μL of distilled water to a final concentration of 1 mg/mL.

Concentration: 1.0 mg/mL after reconstitution

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store lyophilized at 2-8 °C or at -20 °C long term. After reconstitution store the antibody undiluted at 2-8 °C for up to one month or in aliquots at -20 °C long term.

Détails sur IKZF4

Antigène: IKZF4 (IKAROS Family Zinc Finger 4 (Eos) (IKZF4))

Autre désignation: ZNFN1A4 / IKZF4 / EOS (IKZF4 Produits)

Synonymes: anticorps A630026H08Rik, anticorps Eos, anticorps Zfpn1a4, anticorps Znfn1a4, anticorps EOS, anticorps ZNFN1A4, anticorps IKAROS family zinc finger 4, anticorps Ikzf4, anticorps IKZF4

Sujet: IKZF4 also called ZNFN1A4 is a DNA-binding protein that binds to the 5'GGGAATRCC-3' Ikaros-binding sequence and acts as transcriptional repressor. It interacts with SPI1 and MITF to repress transcription of the CTSK and ACP5 promoters via recruitment of corepressors SIN3A and CTBP2 and may be involved in the development of central and peripheral nervous systems. Highly expressed in skeletal muscle, low levels of expression in heart, thymus, kidney, liver, and spleen. Expressed in the hematopoietic cell lines MOLT-4, NALM-6 and K-562. Highly expressed in THP-1 and M-07e cell lines, which have characteristics of myeloid and early megakaryocytic cells respectively.Synonyms: Ikaros family zinc finger protein 4, KIAA1782, Zinc finger protein Eos

ID gène: 64375

NCBI Accession: NP_071910