PRC1 anticorps (Middle Region)
Aperçu rapide pour PRC1 anticorps (Middle Region) (ABIN1449936)
Antigène
Voir toutes PRC1 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- Middle Region
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Réactivité croisée (Details)
- Species reactivity (tested):Human, Mouse, Rat.
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Purification
- Affinity chromatography purified via peptide column
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Immunogène
- 19 amino acid synthetic peptide near the center of Human PRC1
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Isotype
- IgG
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Concentration
- 1.0 mg/mL
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Buffer
- PBS containing 0.02 % Sodium Azide as preservative
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freezing and thawing.
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Stock
- 4 °C/-20 °C
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Stockage commentaire
- Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- PRC1 (Protein Regulator of Cytokinesis 1 (PRC1))
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Autre désignation
- PRC1
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Sujet
- PRC1 (Protein Regulator of Cytokinesis 1) is a key regulator of cytokinesis and has been identified as a substrate for several cyclin-dependent kinases (CDKs). High levels of PRC1 expression occurs during S and G2/M and drops dramatically after mitosis exit and G1 entry. It is located in the nucleus during interphase and binds to the midzone of mitotic spindles during anaphase and is localized to the cell midbody during cytokinesis. Depletion of PRC1 has been shown to prevent cellular cleavage, but it has no effect on nuclear division, demonstrating the importance of PRC1 in mitosis.Synonyms: ASE1, Protein regulator of cytokinesis 1
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ID gène
- 9055
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NCBI Accession
- NP_003972
Antigène
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