ZFYVE21 anticorps (N-Term)

N° du produit ABIN1449943

Cet anticorps Lapin Polyclonal détecte spécifiquement ZFYVE21 dans WB, IF et EIA. Il présente une réactivité avec des échantillons de Humain, Rat et Souris.

Aperçu rapide pour ZFYVE21 anticorps (N-Term) (ABIN1449943)

Antigène: ZFYVE21 (Zinc Finger, FYVE Domain Containing 21 (ZFYVE21))

Reactivité: Humain, Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ZFYVE21 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF), Enzyme Immunoassay (EIA)

Détail du produit anti-ZFYVE21 anticorps

Épitope: N-Term

Purification: Affinity chromatography purified via peptide column

Immunogène: 15 amino acid synthetic peptide near the amino terminus of Human ZF21

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: PBS containing 0.02 % Sodium Azide as preservative

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur ZFYVE21

Antigène: ZFYVE21 (Zinc Finger, FYVE Domain Containing 21 (ZFYVE21))

Autre désignation: ZFYVE21

Sujet: ZF21 was initially identified as protein that could bind to the cytoplasmic tail of MT1-MMP (Membrane-type 1 matrix metalloproteinase), a potent invasion-promoting protease. ZF21 is a member of a protein family characterized by the presence of a phosphatidylinositol 3-phosphate-binding FYVE domain and regulates focal adhesions (FAs) and cell movement. Knockdown of ZF21 expression resulted in a delay of FA disassembly following induction of synchronous disassembly of FAs by nocodazole treatment, suggesting that ZF21 is involved in FA disassembly. ZF21 contains a noncanonical pleckstrin homology domain that is a possible therapeutic target to treat metastatic cancer.Synonyms: Zinc finger FYVE domain-containing protein 21

ID gène: 79038

NCBI Accession: NP_001185882