RAB21 anticorps (C-Term)

N° du produit ABIN1449947

L’anticorps anti-RAB21 Polyclonal Lapin est utilisé pour la détection de RAB21 dans des échantillons de Humain, Rat et Souris. Il a été validé pour WB, IF et EIA.

Aperçu rapide pour RAB21 anticorps (C-Term) (ABIN1449947)

Antigène: RAB21 (RAB21, Member RAS Oncogene Family (RAB21))

Reactivité: Humain, Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RAB21 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF), Enzyme Immunoassay (EIA)

Détail du produit anti-RAB21 anticorps

Épitope: C-Term

Réactivité croisée (Details): Species reactivity (tested):Human, Mouse, Rat.

Purification: Affinity chromatography purified via peptide column

Immunogène: 19 amino acid synthetic peptide near the carboxy terminus of Human RAB21

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: PBS containing 0.02 % Sodium Azide as preservative

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur RAB21

Antigène: RAB21 (RAB21, Member RAS Oncogene Family (RAB21))

Autre désignation: RAB21

Sujet: RAB21 is a member of a subfamily of small GTP-binding protein genes of the Ras superfamily that plays an important role in intracellular vesicular targeting. In non-polarized Caco-2 cells, RAB21 showed a general endoplasmic reticulum (ER)-like localization, while in polarized cells, RAB21 localized to apical vesicles. RAB21 has been shown to associate with integrin subunits and to be important for receptor entry into cells via RAB5/RAB21 endosomes. The GTPase-activating protein p120RasGAP regulates cell motility by controlling the return of the endocytosed integrins to the plasma membrane by competing with RAB21 for binding to overlapping sites on the α-tail of endocytosed integrin.Synonyms: KIAA0118, Rab-21, Ras-related protein Rab-21

ID gène: 23011

NCBI Accession: NP_055814