PLA1A anticorps (C-Term)

N° du produit ABIN1449969

Cet anticorps anti-PLA1A est un anticorps Lapin Polyclonal détectant PLA1A dans WB, IF et EIA. Adapté pour Humain et Rat.

Aperçu rapide pour PLA1A anticorps (C-Term) (ABIN1449969)

Antigène: PLA1A (Phospholipase A1 Member A (PLA1A))

Reactivité: Humain, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PLA1A est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF), Enzyme Immunoassay (EIA)

Détail du produit anti-PLA1A anticorps

Épitope: C-Term

Réactivité croisée (Details): Species reactivity (tested):Human, Rat.

Purification: Affinity chromatography purified via peptide column

Immunogène: 17 amino acid synthetic peptide near the carboxy terminus of Human PLA1A

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: PBS containing 0.02 % Sodium Azide as preservative

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur PLA1A

Antigène: PLA1A (Phospholipase A1 Member A (PLA1A))

Autre désignation: PLA1A

Sujet: PLA1A is a phospholipase that hydrolyzes fatty acids at the sn-1 position of phosphatidylserine and 1-acyl-2-lysophosphatidylserine. This secreted protein hydrolyzes phosphatidylserine (PS) in liposomes and can also hydrolyze PS in apoptotic cells and activate platelets where the resulting 2-acyl-lysophosphatidylserine acts as a lipid mediator for mast cells, T cells, and neural cells, suggesting that a major function of PLA1A may be the production of lysophospholipid mediators. PLA1A is upregulated in rat peripheral blood cells bearing long-term surviving cardiac allograft. PLA1A is also expressed in human THP-1-derived macrophages and this expression is upregulated in cells treated with lipopolysaccharide, a TLR4 ligand. This upregulation is inhibited with corticosteroids, which are often used at high dosages to suppress chronic allograft rejection.Synonyms: NMD, PSPLA1, Phospholipase A1 member A

Poids moléculaire: 50 kDa

ID gène: 51365

NCBI Accession: NP_056984