ATG2B anticorps (N-Term)

N° du produit ABIN1449993

Cet anticorps anti-ATG2B Polyclonal Lapin (ABIN1449993) détecte spécifiquement ATG2B dans WB et EIA. L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour ATG2B anticorps (N-Term) (ABIN1449993)

Antigène: ATG2B (Autophagy Related 2B (ATG2B))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ATG2B est non-conjugé

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Détail du produit anti-ATG2B anticorps

Épitope: N-Term

Purification: Affinity chromatography purified via peptide column

Immunogène: A 19 amino acid synthetic peptide near the amino terminus of Human ATG2B

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: PBS containing 0.02 % Sodium Azide as preservative

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur ATG2B

Antigène: ATG2B (Autophagy Related 2B (ATG2B))

Autre désignation: ATG2B

Sujet: Autophagy, the process of bulk degradation of cellular proteins through an autophagosomic-lysosomal pathway is important for normal growth control and may be defective in tumor cells. It is involved in the preservation of cellular nutrients under starvation conditions as well as the normal turnover of cytosolic components. This process is negatively regulated by TOR (Target of rapamycin) through phosphorylation of autophagy protein APG1. Another member of the autophagy family of proteins is ATG2B, one of two homologs of ATG2 that is essential for autophagosome formation and important for regulation of size and distribution of lipid droplets. Relatively high rates of ATG2B mutations were observed in gastric and colorectal carcinomas, suggesting that deregulating the autophagy process may contribute to cancer development.Synonyms: Autophagy related 2 homolog B

Poids moléculaire: 229 kDa

ID gène: 55102

NCBI Accession: NP_060506