BCAR3 anticorps (N-Term)

N° du produit ABIN1449996

Cet anticorps anti-BCAR3 Polyclonal Lapin (ABIN1449996) détecte spécifiquement BCAR3 dans WB, IF et EIA. L’anticorps est réactif avec des échantillons de Humain, Souris et Rat.

Aperçu rapide pour BCAR3 anticorps (N-Term) (ABIN1449996)

Antigène: BCAR3 (Breast Cancer Anti-Estrogen Resistance 3 (BCAR3))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp BCAR3 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF), Enzyme Immunoassay (EIA)

Détail du produit anti-BCAR3 anticorps

Épitope: N-Term

Purification: Affinity chromatography purified via peptide column

Immunogène: A 16 amino acid synthetic peptide near the amino terminus of Human BCAR3

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: PBS containing 0.02 % Sodium Azide as preservative

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur BCAR3

Antigène: BCAR3 (Breast Cancer Anti-Estrogen Resistance 3 (BCAR3))

Autre désignation: BCAR3 / SH2D3B

Sujet: Breast cancer anti-estrogen resistance 3 (BCAR3) was identified in the search for genes involved in the development of estrogen resistance. It contains a putative src homology 2 (SH2) domain and is partly homologous to the cell division cycle protein CDC48. BCAR3 is a binding partner with Cas, an adapter molecule that plays a role in cell proliferation, survival, cell adhesion, and mobility. BCAR3 functions synergistically with Cas to enhance Src activation and promote cell migration, and has been suggested to regulate Cas/Src association, Src kinase activity, and breast cancer adhesion signaling.Synonyms: Breast cancer anti-estrogen resistance protein 3, NSP2, Novel SH2-containing protein 2, SH2 domain-containing protein 3B

Poids moléculaire: 91 kDa

ID gène: 8412

NCBI Accession: NP_003558