TOX anticorps (N-Term)

N° du produit ABIN1449998

L’anticorps Lapin Polyclonal anti-TOX a été validé pour WB, IF et EIA. Il convient pour détecter TOX dans des échantillons de Humain.

Aperçu rapide pour TOX anticorps (N-Term) (ABIN1449998)

Antigène: TOX (Thymus High Mobility Group Box Protein (TOX))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TOX est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF), Enzyme Immunoassay (EIA)

Détail du produit anti-TOX anticorps

Épitope: N-Term

Purification: Affinity chromatography purified via peptide column

Immunogène: A 17 amino acid synthetic peptide near the amino terminus of Human TOX

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: PBS containing 0.02 % Sodium Azide as preservative

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur TOX

Antigène: TOX (Thymus High Mobility Group Box Protein (TOX))

Autre désignation: TOX

Sujet: TOX (thymocyte selection-associated high mobility group (HMG) box protein) is a member of the HMG box family of DNA-binding proteins and likely plays a role in the regulation of T-cell development (1,2). It is a 526 amino acid nuclear protein and the expression of TOX is upregulated by pre-T cell receptor (pre-TCR) and TCR activation in immature thymocytes. TOX-mediated positive selection is associated with up-regulation of RUNX3 and is calcineurin dependent. TOX-dependent transition to the CD4+CD8 stage is required for development of class II major histocompatibility complex-specific T cells.Synonyms: KIAA0808, Thymocyte selection-associated high mobility group box protein TOX, Thymus high mobility group box protein TOX

Poids moléculaire: 58 kDa

ID gène: 9760

NCBI Accession: NP_055544