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TOX anticorps (N-Term)

TOX Reactivité: Humain WB, IF, EIA Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN1449998
  • Antigène Voir toutes TOX Anticorps
    TOX (Thymus High Mobility Group Box Protein (TOX))
    Épitope
    • 5
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    Reactivité
    • 16
    • 6
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Humain
    Hôte
    • 17
    Lapin
    Clonalité
    • 16
    • 1
    Polyclonal
    Conjugué
    • 13
    • 2
    • 1
    • 1
    Cet anticorp TOX est non-conjugé
    Application
    • 11
    • 7
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF), Enzyme Immunoassay (EIA)
    Purification
    Affinity chromatography purified via peptide column
    Immunogène
    A 17 amino acid synthetic peptide near the amino terminus of Human TOX
    Isotype
    IgG
    Top Product
    Discover our top product TOX Anticorps primaire
  • Indications d'application
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Concentration
    1.0 mg/mL
    Buffer
    PBS containing 0.02 % Sodium Azide as preservative
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Conseil sur la manipulation
    Avoid repeated freezing and thawing.
    Stock
    4 °C/-20 °C
    Stockage commentaire
    Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • Antigène
    TOX (Thymus High Mobility Group Box Protein (TOX))
    Autre désignation
    TOX (TOX Produits)
    Synonymes
    anticorps TOX1, anticorps 1700007F02Rik, anticorps thymocyte selection associated high mobility group box, anticorps thymocyte selection-associated high mobility group box, anticorps TOX, anticorps Tox
    Sujet
    TOX (thymocyte selection-associated high mobility group (HMG) box protein) is a member of the HMG box family of DNA-binding proteins and likely plays a role in the regulation of T-cell development (1,2). It is a 526 amino acid nuclear protein and the expression of TOX is upregulated by pre-T cell receptor (pre-TCR) and TCR activation in immature thymocytes. TOX-mediated positive selection is associated with up-regulation of RUNX3 and is calcineurin dependent. TOX-dependent transition to the CD4+CD8 stage is required for development of class II major histocompatibility complex-specific T cells.Synonyms: KIAA0808, Thymocyte selection-associated high mobility group box protein TOX, Thymus high mobility group box protein TOX
    Poids moléculaire
    58 kDa
    ID gène
    9760
    NCBI Accession
    NP_055544
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