NDFIP1 anticorps (N-Term)

N° du produit ABIN1450002

Détail du produit anti-NDFIP1 anticorps

Antigène: NDFIP1 (Nedd4 Family Interacting Protein 1 (NDFIP1))

Épitope: N-Term

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp NDFIP1 est non-conjugé

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Purification: Affinity chromatography purified via peptide column

Immunogène: A 19 amino acid synthetic peptide near the amino terminus of Human NDFIP1

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: PBS containing 0.02 % Sodium Azide as preservative

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur NDFIP1

Antigène: NDFIP1 (Nedd4 Family Interacting Protein 1 (NDFIP1))

Autre désignation: NDFIP1 (NDFIP1 Produits)

Synonymes: anticorps zgc:55546, anticorps wu:fc17e11, anticorps n4wbp5, anticorps MGC108163, anticorps ndfip1, anticorps NDFIP1, anticorps N4WBP5, anticorps 0610010M22Rik, anticorps N4wbp5, anticorps Nedd4 family interacting protein 1, anticorps Nedd4 WW domain-binding protein 5, anticorps ndfip1, anticorps NDFIP1, anticorps n4wbp5, anticorps Ndfip1

Sujet: The NEDD4 family-interacting protein 1 (NDFIP1) belongs to a small group of evolutionarily conserved proteins with three transmembrane domains and is an integral Golgi membrane protein. It is a potential target for ubiquitination by the Nedd4 family of proteins. NDFIP1 is strongly expressed in surviving neurons following acute cortical brain injury, and overexpression in cultured cortical neurons increased survival following growth factor starvation, suggesting that NDFIP1 may play a role in neuronal survival. NDFIP1 and the related protein NDFIP2 are thought to interact with and regulate multiple components of the EGF and PTEN/Akt signaling pathways. Recent studies suggest that NDFIP1 may also play a role in Th17 differentiation by limiting the production of proinflammatory cytokines.Synonyms: N4WBP5, NEDD4 family-interacting protein 1, PSEC0192, PSEC0223

Poids moléculaire: 24 kDa

ID gène: 80762

NCBI Accession: NP_085048

Pathways: Transition Metal Ion Homeostasis, Regulation of Leukocyte Mediated Immunity, Production of Molecular Mediator of Immune Response, Negative Regulation of Transporter Activity