FAM193B anticorps (N-Term)

N° du produit ABIN1450012

Détail du produit anti-FAM193B anticorps

Antigène: FAM193B (Family with Sequence Similarity 193, Member B (FAM193B))

Épitope: N-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp FAM193B est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF), Enzyme Immunoassay (EIA)

Purification: Affinity chromatography purified via peptide column

Immunogène: 16 amino acid synthetic peptide near the amino terminus of Human FAM193B

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: PBS containing 0.02 % Sodium Azide as preservative

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur FAM193B

Antigène: FAM193B (Family with Sequence Similarity 193, Member B (FAM193B))

Autre désignation: FAM193B (FAM193B Produits)

Synonymes: anticorps IRIZIO, anticorps Kiaa1931, anticorps family with sequence similarity 193 member B, anticorps family with sequence similarity 193, member B, anticorps FAM193B, anticorps Fam193b

Sujet: FAM193B, also known as IRIZIO, was initially identified as a protein that is upregulated in alveolar rhabdomyosarcoma (ARMS), a type of fast-growing tumor characterized by chromosomal translocations fusing the PAX3 or PAX7 gene with that of FOXO1. It has been suggested that, in addition to the PAX3-FOXO1 gene fusion, disruption of the Rb and p53 pathways is required for full ARMS tumorigenesis. In PAX3-FOXO1-expressing primary mouse fibroblasts that possessed a defective p53 pathway, FAM193B expression enabled the tumorigenic transformation, suggesting that FAM193B may contribute to rhabdomyosarcomagenesis in humans.Synonyms: Family with sequence similarity 193 member B, IRIZIO

Poids moléculaire: 99 kDa

ID gène: 54540

UniProt: Q96PV7