BIRC6 anticorps (C-Term)

N° du produit ABIN1450019

L’anticorps anti-BIRC6 Polyclonal Lapin est utilisé pour la détection de BIRC6 dans des échantillons de Humain. Il a été validé pour IHC (p) et EIA.

Aperçu rapide pour BIRC6 anticorps (C-Term) (ABIN1450019)

Antigène: BIRC6 (Baculoviral IAP Repeat-Containing 6 (BIRC6))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp BIRC6 est non-conjugé

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Détail du produit anti-BIRC6 anticorps

Épitope: C-Term

Purification: Affinity chromatography purified via peptide column

Immunogène: A 17 amino acid synthetic peptide near the carboxy terminus of Human BIRC6

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: PBS containing 0.02 % Sodium Azide as preservative

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur BIRC6

Antigène: BIRC6 (Baculoviral IAP Repeat-Containing 6 (BIRC6))

Autre désignation: BIRC6

Sujet: Apoptosis, or programmed cell death, is related to many diseases, such as cancer. Apoptosis is triggered by a variety of stimuli including members in the TNF family and can be prevented by the inhibitor of apoptosis (IAP) proteins. IAP proteins form a conserved gene family that binds to and inhibits cell death proteases. BRUCE, also known as BIRC6, is an IAP family member protein with a BIR (baculoviral inhibition of apoptosis protein repeat) domain and a UBCc (ubiquitin-conjugating enzyme E2, catalytic) domain. BRUCE regulates p53 and the mitochondrial pathway of apoptosis by facilitating the degradation of apoptotic proteins such as Caspase-9 and SMAC by ubiquitination.Synonyms: Apollon, Baculoviral IAP repeat-containing protein 6, KIAA1289, Ubiquitin-conjugating BIR domain enzyme apollon

Poids moléculaire: 534 kDa

ID gène: 57448

NCBI Accession: NP_057336