PANX1 anticorps (N-Term)

N° du produit ABIN1450027

Cet anticorps Lapin Polyclonal détecte spécifiquement PANX1 dans WB et EIA. Il présente une réactivité envers Humain, Rat et Souris.

Aperçu rapide pour PANX1 anticorps (N-Term) (ABIN1450027)

Antigène: PANX1 (Pannexin 1 (PANX1))

Reactivité: Humain, Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PANX1 est non-conjugé

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Détail du produit anti-PANX1 anticorps

Épitope: N-Term

Purification: Affinity chromatography purified via peptide column

Immunogène: Rabbit polyclonal PANX1 antibody was raised against a 17 amino acid peptide near the amino terminus of human PANX1.

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: PBS containing 0.02 % Sodium Azide as preservative

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: -20 °C

Stockage commentaire: Store the antibody (in aliquots) at -20 °C.

Détails sur PANX1

Antigène: PANX1 (Pannexin 1 (PANX1))

Autre désignation: PANX1

Sujet: The pannexin gene family encodes a second class of putative gap junction proteins and are highly conserved in invertebrates and mammals. Pannexins (Panx) are four-pass transmembrane proteins that oligomerize to form large pore ion and metabolite-permeable channels. Pannexin-1 (PANX1) and Pannexin-3 are closely related, while Pannexin-2 is a more distant relation. PANX1 is a transmembrane protein that forms a mechanosensitive ATP-permeable channel between adjacent cells and in the endoplasmic reticulum. PANX1 may play a role as a Ca2+ -leak channel to regulate ER Ca2+ homeostasis and regulates neural stem and progenitor cell proliferation.Synonyms: MRS1, PX1, Pannexin 1, Pannexin-1, UNQ2529

Poids moléculaire: 47 kDa

ID gène: 24145

NCBI Accession: NP_056183