UHRF1BP1 anticorps (Middle Region)
Aperçu rapide pour UHRF1BP1 anticorps (Middle Region) (ABIN1450049)
Antigène
Voir toutes UHRF1BP1 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- Middle Region
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Réactivité croisée (Details)
- Species reactivity (tested):Human, Mouse.
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Purification
- Affinity chromatography purified via peptide column
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Immunogène
- 17 amino acid synthetic peptide near the center of Human UHRF1BP1
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Isotype
- IgG
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Concentration
- 1.0 mg/mL
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Buffer
- PBS containing 0.02 % Sodium Azide as preservative
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freezing and thawing.
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Stock
- 4 °C/-20 °C
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Stockage commentaire
- Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- UHRF1BP1 (UHRF1 Binding Protein 1 (UHRF1BP1))
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Autre désignation
- UHRF1BP1
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Sujet
- The Ubiquitin-like containing PHD and RING finger domains 1-binding protein 1 (UHRF1BP1), also known as ICBP90, is a transcription and cell cycle regulator. It specifically binds to the histone H3 N-terminal tail when methylated on K9 by two functional domains, a PHD finger that defines the binding specificity and an SRA (SET- and RING-associated) domain that promotes binding activity. UHRF1BP1 is required for proper heterochromatin formation in mammalian cells. Furthermore, UHRF1BP1 is thought to be a pivotal target for the ERK1/2 signaling pathway to control the proliferation of Jurkat T cells.Synonyms: ICBP90-binding protein 1, UHRF1 binding protein 1, Ubiquitin-like containing PHD and RING finger domains 1-binding protein 1
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ID gène
- 54887
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NCBI Accession
- NP_060224
Antigène
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