HIGD1A anticorps (N-Term)
Aperçu rapide pour HIGD1A anticorps (N-Term) (ABIN1450057)
Antigène
Voir toutes HIGD1A AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- N-Term
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Réactivité croisée (Details)
- Species reactivity (tested):Human.
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Purification
- Affinity chromatography purified via peptide column
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Immunogène
- 19 amino acid synthetic peptide near the amino terminus of Human HIG1
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Isotype
- IgG
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Concentration
- 1.0 mg/mL
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Buffer
- PBS containing 0.02 % Sodium Azide as preservative
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freezing and thawing.
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Stock
- 4 °C/-20 °C
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Stockage commentaire
- Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- HIGD1A (HIG1 Hypoxia Inducible Domain Family, Member 1A (HIGD1A))
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Autre désignation
- HIG1
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Sujet
- HIG1 and HIG2 (Hypoxia-inducible gene 1 and 2, respectively) are known to be induced by hypoxic conditions. HIG1 is induced by hypoxia and by glucose deprivation in cultured cells. In addition, tumor xenografts derived from human cervical cancer cells display increased expression of HIG1 and HIG2 when they are deprived of oxygen. Unlike HIG2, which is ubiquitously expressed and might be an activator and target of the canonical Wnt pathway, the function and the mechanisms underlying its regulation of HIG1 still remained unknown. The putative link between hypoxia and an oncogenic signaling pathway might play an important role in tumorigenesis.Synonyms: HIGD1A, HSPC010, Hypoxia-inducible gene 1 protein, hypoxia inducible domain family 1A
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ID gène
- 25994
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NCBI Accession
- NP_001093138
Antigène
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