C2orf40 anticorps (C-Term)

N° du produit ABIN1450064

L’anticorps Lapin Polyclonal anti-C2orf40 a été validé pour WB, IF et EIA. Il convient pour détecter C2orf40 dans des échantillons de Humain, Souris et Rat.

Aperçu rapide pour C2orf40 anticorps (C-Term) (ABIN1450064)

Antigène: C2orf40 (Chromosome 2 Open Reading Frame 40 (C2orf40))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp C2orf40 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF), Enzyme Immunoassay (EIA)

Détail du produit anti-C2orf40 anticorps

Épitope: C-Term

Réactivité croisée (Details): Species reactivity (tested):Human, Mouse, Rat.

Purification: Affinity chromatography purified via peptide column

Immunogène: 20 amino acid synthetic peptide near the carboxy terminus of Human ECRG4

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: PBS containing 0.02 % Sodium Azide as preservative

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur C2orf40

Antigène: C2orf40 (Chromosome 2 Open Reading Frame 40 (C2orf40))

Autre désignation: Augurin

Sujet: The esophageal cancer-related gene 4 (ECRG4), also known as Augurin, was identified through differential display screening between esophageal cancer and normal tissue. Hypermethylation of CpG sites in the ECRG4 promoter correlate with ECRG4 downregulation in numerous esophageal squamous cell carcinoma tissues.. In transfected cells, overexpression of ECRG4 induced G1 arrest, dephosphorylation of Rb and decreased expression of cyclins D1 and D3. Increased expression of ECRG4 in aged mouse brain is observed compared with young mouse brain. The increased ECRG4 level was accompanied by elevated senescence-associated acidic beta-galactosidase activity, suggesting that ECRG4 is involved in cellular differentiation and senescence.Synonyms: C2orf40, ECRG4

ID gène: 84417