PRICKLE2 anticorps (Middle Region)

N° du produit ABIN1450075

Détail du produit anti-PRICKLE2 anticorps

Antigène: PRICKLE2 (Prickle Homolog 2 (PRICKLE2))

Épitope: Middle Region

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PRICKLE2 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF), Enzyme Immunoassay (EIA)

Réactivité croisée (Details): Species reactivity (tested):Human, Mouse, Rat.

Purification: Affinity chromatography purified via peptide column

Immunogène: 15 amino acid synthetic peptide near the center of human PRICKLE2

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: PBS containing 0.02 % Sodium Azide as preservative

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur PRICKLE2

Antigène: PRICKLE2 (Prickle Homolog 2 (PRICKLE2))

Autre désignation: PRICKLE2 (PRICKLE2 Produits)

Synonymes: anticorps EPM5, anticorps 6230400G14Rik, anticorps 6720451F06Rik, anticorps mpk2, anticorps cb886, anticorps im:7138215, anticorps pk2, anticorps prickle planar cell polarity protein 2, anticorps prickle homolog 2b, anticorps PRICKLE2, anticorps Prickle2, anticorps prickle2b

Sujet: PRICKLE2, also known as Pk2 or EPM5, is a member of a highly conserved protein family that function in the noncanonical WNT signaling pathway which regulates intracellular calcium release and planar cell polarity. Both PRICKLE2 and the related protein PRICKLE1 are expressed in postmitotic neurons and promote neurite outgrowth, and both proteins promote neurite outgrowth via the Dishevelled dependent pathway in C1300 cells. PRICKLE2 localizes to the postsynaptic density and interacts with PSD-95 and NMDA receptors. Defects in the gene encoding PRICKLE2 are associated with autosomal recessive progressive myoclonic epilepsy.Synonyms: PRICKLE-2, Prickle-like protein 2

ID gène: 166336

NCBI Accession: NP_942559