SIK3 anticorps (C-Term)
Aperçu rapide pour SIK3 anticorps (C-Term) (ABIN1450082)
Antigène
Reactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- C-Term
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Réactivité croisée (Details)
- Species reactivity (tested):Human, Mouse, Rat.
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Purification
- Affinity chromatography purified via peptide column
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Immunogène
- 18 amino acid synthetic peptide near the carboxy terminus of human SIK3
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Concentration
- 1.0 mg/mL
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Buffer
- PBS containing 0.02 % Sodium Azide as preservative
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freezing and thawing.
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Stock
- 4 °C/-20 °C
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Stockage commentaire
- Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- SIK3 (SIK Family Kinase 3 (SIK3))
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Autre désignation
- QSK
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Sujet
- Salt-inducible kinase family (SIKs) proteins are thought to have a role in steroidogenesis, adipogenesis or regulation of tumor malignancy. Three members (SIK1, SIK2 and SIK3) in the SIK family have been identified thus far. Their kinase domain sequences are closely homologous to those of AMP-activated protein kinase (AMPK). SIK3 can be phosphorylated by a tumor-suppressor kinase LKB1. It is highly and preferentially expressed in ovarian tumors but not in adenomyosis and leiomyoma and may be a potential diagnostic marker for ovarian cancers.Synonyms: EC=2.7.11.1, KIAA0999, QSK, SIK-3, SIK3, Salt-inducible kinase 3, Serine/threonine-protein kinase QSK
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ID gène
- 23387
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NCBI Accession
- NP_079440
Antigène
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