RAPGEF4 anticorps (N-Term)

N° du produit ABIN1450105

Détail du produit anti-RAPGEF4 anticorps

Antigène: RAPGEF4 (Rap Guanine Nucleotide Exchange Factor (GEF) 4 (RAPGEF4))

Épitope: N-Term

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RAPGEF4 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Réactivité croisée (Details): Species reactivity (tested):Human, Mouse, Rat

Purification: Affinity chromatography purified via peptide column

Immunogène: 15 amino acid synthetic peptide near the amino terminus of human RAPGEF4 / EPAC2

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: PBS containing 0.02 % Sodium Azide as preservative

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur RAPGEF4

Antigène: RAPGEF4 (Rap Guanine Nucleotide Exchange Factor (GEF) 4 (RAPGEF4))

Autre désignation: RAPGEF4 (RAPGEF4 Produits)

Synonymes: anticorps RAPGEF4, anticorps CAMP-GEFII, anticorps CGEF2, anticorps EPAC2, anticorps Nbla00496, anticorps 1300003D15Rik, anticorps 5730402K07Rik, anticorps 6330581N18Rik, anticorps EPAC 2, anticorps Epac-2, anticorps Epac2, anticorps mKIAA4040, anticorps CAMPS, anticorps Cgef2, anticorps Rap guanine nucleotide exchange factor 4, anticorps rap guanine nucleotide exchange factor 4, anticorps Rap guanine nucleotide exchange factor (GEF) 4, anticorps RAPGEF4, anticorps LOC579050, anticorps LOC100551109, anticorps PTRG_05798, anticorps Rapgef4

Sujet: EPAC2, also known as Rap guanine nuclear exchange factor 4 (RAPGEF4) and cAMPGEF-II, is belongs to a family of cyclic adenosine monophosphate (cAMP) binding proteins with guanine nucleotide exchange factor. Like the related protein EPAC1, EPAC2 signaling plays a role in numerous cellular processes such as integrin-mediated cell adhesion, muscle contraction, learning and memory, cell proliferation, and inflammation. Recent evidence suggests that EPAC2 induces synapse remodeling and depression, with mutations in its gene being found in patients with autism.Synonyms: CGEF2, EPAC 2, EPAC2, Exchange factor directly activated by cAMP 2, Exchange protein directly activated by cAMP 2, Rap guanine nucleotide exchange factor 4, cAMP-GEFII, cAMP-regulated guanine nucleotide exchange factor II

ID gène: 11069

NCBI Accession: NP_008954

Pathways: Hormone Transport, Smooth Muscle Cell Migration