MEX3B anticorps (Middle Region)

N° du produit ABIN1450108

Cet anticorps Lapin Polyclonal détecte spécifiquement MEX3B dans WB, IF et EIA. Il présente une réactivité avec des échantillons de Humain, Souris et Rat.

Aperçu rapide pour MEX3B anticorps (Middle Region) (ABIN1450108)

Antigène: MEX3B (Mex-3 Homolog B (MEX3B))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MEX3B est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF), Enzyme Immunoassay (EIA)

Détail du produit anti-MEX3B anticorps

Épitope: Middle Region

Réactivité croisée (Details): Species reactivity (tested):Human, Mouse, Rat.

Purification: Affinity chromatography purified via peptide column

Immunogène: RKHD3 antibody was raised against a 16 amino acid synthetic peptide from near the center of human RKHD3.

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: PBS containing 0.02 % Sodium Azide as preservative

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur MEX3B

Antigène: MEX3B (Mex-3 Homolog B (MEX3B))

Autre désignation: MEX3B / RKHD3

Sujet: Rkhd3, also known as MEX3B is a member of a novel family of four homologous human MEX3 proteins each containing two heterogeneous nuclear ribonucleoprotein K homology (KH) domains and one carboxy-terminal RING finger module. MEX3 proteins, including Rkhd3, are phosphoproteins that bind RNA through their KH domains and shuttle between the nucleus and the cytoplasm via the CRM1 export pathway. These proteins are a novel family of evolutionarily conserved RNA-binding proteins, differentially recruited to P bodies and potentially involved in post-transcriptional regulatory mechanisms. Rkhd3 is thought to act as a mechanism to fine-tune mRNA regulation in early Xenopus development, and with Rkhd4, but not Rkhd1, will co-localize with both the hDcp1a decapping factor and Argonaute (Ago) proteins in processing bodies (P bodies), recently characterized as centers of mRNA turnover.Synonyms: KIAA2009, RING finger and KH domain-containing protein 3, RING finger protein 195, RNA-binding protein MEX3B, RNF195

ID gène: 84206

NCBI Accession: NP_780575