MLIP anticorps (C-Term)
Aperçu rapide pour MLIP anticorps (C-Term) (ABIN1450122)
Antigène
Reactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- C-Term
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Réactivité croisée (Details)
- Species reactivity (tested):Human.
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Purification
- Affinity chromatography purified via peptide column
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Immunogène
- 16 amino acid synthetic peptide near the carboxy terminus of Human MLIP
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Isotype
- IgG
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Concentration
- 1.0 mg/mL
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Buffer
- PBS containing 0.02 % Sodium Azide as preservative
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freezing and thawing.
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Stock
- 4 °C/-20 °C
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Stockage commentaire
- Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- MLIP (Muscular LMNA-Interacting Protein (MLIP))
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Autre désignation
- MLIP
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Sujet
- The muscle-enriched A-type lamin-interacting protein (MLIP) is ubiquitously expressed, although most predominantly in heart, skeletal and smooth muscle, and interacts directly and co-localizes with lamin A and C in the nuclear envelope. MLIP also co-localizes with promyelocytic leukemia (PML) bodies within the nucleus. Decreasing lamin A/C expression with siRNA results in the upregulation and mislocalization of MLIP, suggesting that MLIP localization to the nuclear envelope is dependent on the lamin proteins. It has been suggested that MLIP may function as a tethering protein linking LMNA to factors within the nuclear envelope of within PML bodiesSynonyms: C6orf142, Muscle enriched A-type lamin interacting protein
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ID gène
- 90523
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NCBI Accession
- NP_612636
Antigène
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