C9ORF116 anticorps (N-Term)

N° du produit ABIN1450123

Cet anticorps Lapin Polyclonal détecte spécifiquement C9ORF116 dans WB, EIA et IF. Il présente une réactivité envers Humain et Souris.

Aperçu rapide pour C9ORF116 anticorps (N-Term) (ABIN1450123)

Antigène: C9ORF116 (Chromosome 9 Open Reading Frame 116 (C9ORF116))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp C9ORF116 est non-conjugé

Application: Western Blotting (WB), Enzyme Immunoassay (EIA), Immunofluorescence (IF)

Détail du produit anti-C9ORF116 anticorps

Épitope: N-Term

Purification: Affinity chromatography purified via peptide column

Immunogène: 16 amino acid synthetic peptide near the amino terminus of Human PIERCE1

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: PBS containing 0.02 % Sodium Azide as preservative

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur C9ORF116

Antigène: C9ORF116 (Chromosome 9 Open Reading Frame 116 (C9ORF116))

Autre désignation: C9orf116

Sujet: PIERCE1, also known as C9orf116, is an important p53 target gene contributing to normal DNA damage response and may play crucial roles in maintaining genomic integrity against genotoxic stresses, including UVC irradiation (1,2). PIERCE1 exists as two alternatively spliced isoforms and is predominantly expressed in human small cell lung cancer (3-4). PIERCE1 knockdown induces down-regulation of proapoptotic genes including Ei24, Apaf1 and PTEN, suggesting that PIERCE1 is a proapoptotic gene. It is helpful for in-depth understanding of p53 pathways and the design of new cancer therapies (1-3).Synonyms: Pierce1, p53-induced expression in RB-null cells protein 1

ID gène: 138162

NCBI Accession: NP_001041730