Nkx2-2 anticorps (Middle Region)

N° du produit ABIN1450127

L’anticorps Lapin Polyclonal anti-Nkx2-2 a été validé pour IF, IHC (p), WB et EIA. Il convient pour détecter Nkx2-2 dans des échantillons de Humain, Souris et Rat.

Aperçu rapide pour Nkx2-2 anticorps (Middle Region) (ABIN1450127)

Antigène: Nkx2-2 (NK2 Homeobox 2 (Nkx2-2))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Nkx2-2 est non-conjugé

Application: Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB), Enzyme Immunoassay (EIA)

Détail du produit anti-Nkx2-2 anticorps

Épitope: Middle Region

Réactivité croisée (Details): Species reactivity (tested):Human, Mouse, Rat.

Purification: Affinity chromatography purified via peptide column

Immunogène: 19 amino acid synthetic peptide near the center of Human NKX2-2

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: PBS containing 0.02 % Sodium Azide as preservative

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur Nkx2-2

Antigène: Nkx2-2 (NK2 Homeobox 2 (Nkx2-2))

Autre désignation: NKX2-2

Sujet: NKX2-2 (NK2 homeobox 2) is a member of a family of transcription factors that are involved in embryonic development and cell fate. NKX2-2 is crucial in the development of pancreatic islet cell differentiation and activates the ghrelin-promoter in these cells. NKX2-2 is expressed at the onset of pancreatic epithelium formation and becomes restricted to mature alpha-, beta- and PP cells, and in NKX2-2-null mice embryos, all beta-cells and most a-cells are replaced by ghrelin-positive cells. NKX2-2 is also thought to be involved in ventral neuronal patterning and floor plate development and commissural axon guidance.Synonyms: Homeobox protein Nkx-2.2, NK2 transcription factor related, NKX2.2, NKX2B, locus 2

ID gène: 4821

NCBI Accession: NP_002500

Pathways: Dopaminergic Neurogenesis