SIGLEC15 anticorps (N-Term)

N° du produit ABIN1450134

Détail du produit anti-SIGLEC15 anticorps

Antigène: SIGLEC15 (Sialic Acid Binding Ig-Like Lectin 15 (SIGLEC15))

Épitope: N-Term

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SIGLEC15 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Réactivité croisée (Details): Species reactivity (expected):Human, Mouse, Rat.

Purification: Affinity chromatography purified via peptide column

Immunogène: 15 amino acid synthetic peptide near the amino terminus of Human SIGLEC15

Isotype: IgG

Information d'application

Indications d'application: WB: 1 - 2 ug/mL, IHC: 2.5 ug/mL
Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: PBS containing 0.02 % Sodium Azide as preservative

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur SIGLEC15

Antigène: SIGLEC15 (Sialic Acid Binding Ig-Like Lectin 15 (SIGLEC15))

Autre désignation: SIGLEC15 / CD33L3 (SIGLEC15 Produits)

Synonymes: anticorps RGD1565948, anticorps CD33L3, anticorps HsT1361, anticorps SIGLEC-15, anticorps Cd33l3, anticorps EG620235, anticorps SIGLEC-I, anticorps sialic acid binding Ig-like lectin 15, anticorps sialic acid binding Ig like lectin 15, anticorps Siglec15, anticorps SIGLEC15

Sujet: Siglecs are vertebrate cell-surface lectins that recognize sialylated glycans and are involved in many physiological processes, such as glycoprotein turnover, cellular trafficking, and pathogen recognition. Most Siglecs are expressed on cells of the immune system. SIGLEC15 is a type-I transmembrane protein consisting of two immunoglobulin (Ig)-like domains, a transmembrane domain containing a lysine residue, and a short cytoplasmic tail. SIGLEC15 can interact with the activating adaptor molecules DAP12/10. Its activating signaling potential and unique preference for glycan recognition implies that SIGLEC15 may be involved in the immune surveillance of tumors and probably plays a conserved, regulatory role in the immune system of vertebrates.Synonyms: CD33 antigen-like 3, SIGLEC-15, Sialic acid-binding Ig-like lectin 15

ID gène: 284266

NCBI Accession: NP_998767