VKORC1 anticorps (N-Term)

N° du produit ABIN1450145

L’anticorps anti-VKORC1 Polyclonal Lapin est utilisé pour la détection de VKORC1 dans des échantillons de Humain et Souris. Il a été validé pour WB, IF, IHC (p) et EIA.

Aperçu rapide pour VKORC1 anticorps (N-Term) (ABIN1450145)

Antigène: VKORC1 (Vitamin K Epoxide Reductase Complex, Subunit 1 (VKORC1))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp VKORC1 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Détail du produit anti-VKORC1 anticorps

Épitope: N-Term

Purification: Affinity chromatography purified via peptide column

Immunogène: 15 amino acid synthetic peptide near the amino terminus of Human VKORC1

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: PBS containing 0.02 % Sodium Azide as preservative

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur VKORC1

Antigène: VKORC1 (Vitamin K Epoxide Reductase Complex, Subunit 1 (VKORC1))

Autre désignation: VKORC1

Sujet: Vitamin K epoxide reductase complex subunit 1 (VKORC1) is the enzyme that is responsible for reducing vitamin K 2,3-epoxide to the enzymatically activated form which is essential for blood clotting. This enzymatically activated form of vitamin K is a reduced form required for the carboxylation of glutamic acid residues in some blood-clotting proteins. Fatal bleeding can be caused by vitamin K deficiency and by the vitamin K antagonist warfarin, and it is VKORC1 that is sensitive to warfarin. In humans, mutations in this gene can be associated with deficiencies in vitamin-K-dependent clotting factors and, in humans and rats, with warfarin resistance.Synonyms: 3-epoxide reductase subunit 1, MSTP134, MSTP576, UNQ308/PRO351, VKOR, Vitamin K epoxide reductase complex subunit 1, Vitamin K1 2

ID gène: 79001

NCBI Accession: NP_076869