BOK anticorps (N-Term)

N° du produit ABIN1450152

Détail du produit anti-BOK anticorps

Antigène: BOK (BCL2-Related Ovarian Killer (BOK))

Épitope: N-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp BOK est non-conjugé

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Purification: Affinity chromatography purified via peptide column

Immunogène: 16 amino acid synthetic peptide near the amino terminus of Human BOK

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: PBS containing 0.02 % Sodium Azide as preservative

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur BOK

Antigène: BOK (BCL2-Related Ovarian Killer (BOK))

Autre désignation: BOK / BCL2L9 (BOK Produits)

Synonymes: anticorps BOK, anticorps bok, anticorps zgc:100979, anticorps zgc:64041, anticorps BCL2L9, anticorps BOKL, anticorps Bok-BH3, anticorps AI847676, anticorps AU021146, anticorps matador, anticorps mtd, anticorps BOK, BCL2 family apoptosis regulator, anticorps BCL2-related ovarian killer a, anticorps BCL2-related ovarian killer b, anticorps BCL2-related ovarian killer, anticorps BOK, anticorps boka, anticorps bokb, anticorps Bok

Sujet: Apoptosis plays a major role in normal organism development, tissue homeostasis, and removal of damaged cells. Disruption of this process has been implicated in a variety of diseases such as cancer. The Bcl-2 family of proteins is comprised of critical regulators of apoptosis that can be divided into two classes: those that inhibit apoptosis and those that promote cell death. BOK, a pro-apoptotic Bcl-2 family member, was initially identified in the ovary, and was found to interact with other Bcl-2 family members such as Mcl-1 and Bfl-1. BOK expression is high during early placental development, suggesting that it may also play a role in regulating trophoblast cell proliferation.Synonyms: Bcl-2-like protein 9, Bcl-2-related ovarian killer protein, Bcl2-L-9, Hbok

ID gène: 666

Pathways: Positive Regulation of Endopeptidase Activity