PTCHD2 anticorps (N-Term)

N° du produit ABIN1450154

L’anticorps anti-PTCHD2 Polyclonal Lapin est utilisé pour la détection de PTCHD2 dans des échantillons de Humain. Il a été validé pour IHC (p) et EIA.

Aperçu rapide pour PTCHD2 anticorps (N-Term) (ABIN1450154)

Antigène: PTCHD2 (Patched Domain Containing 2 (PTCHD2))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PTCHD2 est non-conjugé

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Détail du produit anti-PTCHD2 anticorps

Épitope: N-Term

Purification: Affinity chromatography purified via peptide column

Immunogène: A 19 amino acid synthetic peptide from near the amino terminus of Human PTCHD2

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: PBS containing 0.02 % Sodium Azide as preservative

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur PTCHD2

Antigène: PTCHD2 (Patched Domain Containing 2 (PTCHD2))

Autre désignation: PTCHD2

Sujet: PTCHD2, also known as DISP3, is the third of three known homologs of the D. melanogaster protein Dispatched. It is a multi-transmembrane protein containing two PTCH/DISP domains and is thought to be involved in the release of lipid-anchored secreted proteins. Like DISP1 and DISP2, DISP3 has been implicated in signaling pathways during embryogenesis, tissue regeneration, and carcinogenesis. It is highly expressed in Purkinje cells, hippocampal neurons, and retinal ganglion cells. Recently, it has been shown that PTCHD2 localizes within the endoplasmic reticulum and colocalizes with cholesterol, and given that its expression is regulated by thyroid hormone (T3), it has been suggested that DISP3 may be a link between thyroid hormone and cholesterol metabolism.Synonyms: DISP3, KIAA1337, Patched domain-containing protein 2, Protein dispatched homolog 3

ID gène: 57540

UniProt: Q9P2K9