IRF2BP2 anticorps (N-Term)

N° du produit ABIN1450159

Cet anticorps Lapin Polyclonal détecte spécifiquement IRF2BP2 dans IHC (p) et EIA. Il présente une réactivité envers Humain.

Aperçu rapide pour IRF2BP2 anticorps (N-Term) (ABIN1450159)

Antigène: IRF2BP2 (Interferon Regulatory Factor 2 Binding Protein 2 (IRF2BP2))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp IRF2BP2 est non-conjugé

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Détail du produit anti-IRF2BP2 anticorps

Épitope: N-Term

Purification: Affinity chromatography purified via peptide column

Immunogène: 17 amino acid synthetic peptide near the amino terminus of human IRF2BP2

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: PBS containing 0.02 % Sodium Azide as preservative

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur IRF2BP2

Antigène: IRF2BP2 (Interferon Regulatory Factor 2 Binding Protein 2 (IRF2BP2))

Autre désignation: IRF2BP2

Sujet: IRF2BP2, like the related protein IRF2BP1, is a co-repressor that interacts specifically with the C-terminal repression domain of Interferon Regulatory Factor 2 (IRF2). IRF2BP2 is a direct target gene of p53 and is involved in cell survival during the p53 stress response, able to impede the p53-mediated transactivation of p21 and Bax. IRF2BP2 is also a co-factor of VGLL4 and is required to induce the expression of vascular endothelial growth factor A (VEGF-A) in muscle. It is normally found in the nucleus of skeletal muscle and cardiac cells, but can be found in the cytoplasm during skeletal muscle differentiation .Synonyms: IRF-2-binding protein 2, IRF-2BP2, Interferon regulatory factor 2-binding protein 2

ID gène: 359948

NCBI Accession: NP_892017