PHOX2B anticorps (Middle Region)

N° du produit ABIN1450171

Cet anticorps Lapin Polyclonal détecte spécifiquement PHOX2B dans WB et EIA. Il présente une réactivité envers Humain, Souris et Rat.

Aperçu rapide pour PHOX2B anticorps (Middle Region) (ABIN1450171)

Antigène: PHOX2B (Paired-Like Homeobox 2b (PHOX2B))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PHOX2B est non-conjugé

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Détail du produit anti-PHOX2B anticorps

Épitope: Middle Region

Purification: Affinity chromatography purified via peptide column

Immunogène: 15 amino acid synthetic peptide near the center of Human PHOX2B

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: PBS containing 0.02 % Sodium Azide as preservative

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur PHOX2B

Antigène: PHOX2B (Paired-Like Homeobox 2b (PHOX2B))

Autre désignation: PHOX2B

Sujet: PHOX2A and PHOX2B (Paired mesoderm homeobox protein) are closely related, paired-homeodomain transcription factors that function as determinants of the noradrenergic phenotype during embryogenesis. PHOX2 proteins are crucial for the regulation of endogenous hydroxylases in neural crest cells and promote sympathetic neuron generation. Human PHOX2B contains one DNA binding homeobox domain and is required for the differentiation of all central and nonperipheral noradrenergic centers in the brain. In contrast, PHOX2A controls only the differentiation of the main noradrenergic center of the brain. Regulation of PHOX2 may have therapeutic utility in aging or disorders involving degeneration of noradrenergic neurons .Synonyms: NBPhox, Neuroblastoma Phox, PHOX2B homeodomain protein, PMX2B, Paired mesoderm homeobox protein 2B, Paired-like homeobox 2B

ID gène: 8929

NCBI Accession: NP_003915