GFRA1 anticorps

N° du produit ABIN1450224

Détail du produit anti-GFRA1 anticorps

Antigène: GFRA1 (GDNF Family Receptor alpha 1 (GFRA1))

Reactivité: Humain

Hôte: Poulet

Clonalité: Polyclonal

Conjugué: Cet anticorp GFRA1 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF)

Specificité: Glial cell line-derived neurotrophic factor (GDNF) andneurturin (NTN) are two structurally related, potent neurotrophic factors thatplay key roles in the control of neuron survival and differentiation. The GFRa-1is a member of the GDNF receptor family. It is a glycosylphosphatidylinositol(GPI)-linked cell surface receptor for both GDNF and NTN, and mediatesactivation of the RET tyrosine kinase receptor (www.ncbi.nlm.nih.gov/gene/2674)

Attributs du produit: Mono- and polyclonal antibodies to human growth factors and neural growth factor receptors.

Purification: GFRa-1 affinity purified

Isotype: IgY

Information d'application

Indications d'application: Westernimmunoblotting, recommended dilution 1:5 000 to 1:10 000, ELISA: 1:80 000 to160 000,IF 1:1000 to 1:2000. Polyclonal antibody working titer has to be established practically for each particularantigen and assay format

Commentaires:

Synonym: RET ligand 1, TGF-beta related neurotrophic factorreceptor 1

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/ml

Buffer: Concentrated ammonium sulphate in PBS pH 7.4

Conseil sur la manipulation: As product is (NH4)2SO4 precipitate, mix well by pipetting or vortexing prior use

Stock: 4 °C

Stockage commentaire: This product is shipped in non-frozen liquid form in ambient conditions

Détails sur GFRA1

Antigène: GFRA1 (GDNF Family Receptor alpha 1 (GFRA1))

Autre désignation: GFRa-1 (GFRA1 Produits)

Synonymes: anticorps gdnfr, anticorps ret1l, anticorps retl1, anticorps trnr1, anticorps gdnfra, anticorps MGC122616, anticorps gfr-alpha-1, anticorps GDNFR, anticorps GDNFRA, anticorps GFR-ALPHA-1, anticorps RET1L, anticorps RETL1, anticorps TRNR1, anticorps GDNFRALPHA, anticorps GFRA1, anticorps AU042498, anticorps gfralpha1a, anticorps zgc:110129, anticorps GDNF family receptor alpha 1, anticorps glial cell line derived neurotrophic factor family receptor alpha 1, anticorps gdnf family receptor alpha 1a, anticorps gfra1, anticorps GFRA1, anticorps Gfra1, anticorps gfra1a

Sujet: Recombinant His-tagged human GFRa-1 protein producedusing CHO-based cell line. For production of hGFRa-1, glycosylphosphatidyl-inositol GPI-anchor was removedand protein was secreted to the cell culture supernatant. Protein was purifiedby Ni-affinity chromatography following gel-filtration from cell culturesupernatant

UniProt: P56159