NACA anticorps (pSer43)

N° du produit ABIN1450497

Cet anticorps anti-NACA Polyclonal Lapin (ABIN1450497) détecte spécifiquement NACA dans IHC, ELISA et IF. L’anticorps est réactif avec des échantillons de Humain, Souris et Rat.

Aperçu rapide pour NACA anticorps (pSer43) (ABIN1450497)

Antigène: NACA (NACa1) (Nascent Polypeptide Associated Complex alpha 1 (NACa1))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp NACA est non-conjugé

Application: Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Détail du produit anti-NACA anticorps

Épitope: AA 9-58, pSer43

Fonction: NACA (phospho Ser43) Antibody

Specificité: Phospho-NACA (S43) Polyclonal Antibody detects endogenous levels of NACA protein only when phosphorylated at S43.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: The antiserum was produced against synthesized peptide derived from human NACA around the phosphorylation site of Ser43. AA range:9-58

Isotype: IgG

Information d'application

Indications d'application: IHC 1:100 - 1:300. ELISA: 1:5000.. IF 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C/1 year

Date de péremption: 12 months

Détails sur NACA

Antigène: NACA (NACa1) (Nascent Polypeptide Associated Complex alpha 1 (NACa1))

Autre désignation: NACA

Sujet:

Synonyms: NACA, HSD48, Nascent polypeptide-associated complex subunit alpha, NAC-alpha, Alpha-NAC, allergen Hom s 2

Background: This gene encodes a protein that associates with basic transcription factor 3 (BTF3) to form the nascent polypeptide-associated complex (NAC). This complex binds to nascent proteins that lack a signal peptide motif as they emerge from the ribosome, blocking interaction with the signal recognition particle (SRP) and preventing mistranslocation to the endoplasmic reticulum. This protein is an IgE autoantigen in atopic dermatitis patients. Alternative splicing results in multiple transcript variants, but the full length nature of some of these variants, including those encoding very large proteins, has not been determined. There are multiple pseudogenes of this gene on different chromosomes. [provided by RefSeq, Feb 2016],

Gene Name: NACA

Protein Name: Nascent polypeptide-associated complex subunit alpha

Poids moléculaire: 23 kDa

ID gène: 4666

OMIM: 601234

UniProt: Q13765

Pathways: Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development