SIN3B anticorps (AA 221-270)

N° du produit ABIN1450803

Cet anticorps anti-SIN3B Polyclonal Lapin (ABIN1450803) détecte spécifiquement SIN3B dans WB, ELISA et IHC. L’anticorps est réactif avec des échantillons de Humain, Souris et Rat.

Aperçu rapide pour SIN3B anticorps (AA 221-270) (ABIN1450803)

Antigène: SIN3B (SIN3 Transcription Regulator Homolog B (SIN3B))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SIN3B est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Détail du produit anti-SIN3B anticorps

Épitope: AA 221-270

Fonction: Sin3B Antibody

Specificité: Sin3B Polyclonal Antibody detects endogenous levels of Sin3B protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: The antiserum was produced against synthesized peptide derived from human SIN3B. AA range:221-270

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-2000,IHC 1:50-300, ELISA 2000-20000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C/1 year

Date de péremption: 12 months

Détails sur SIN3B

Antigène: SIN3B (SIN3 Transcription Regulator Homolog B (SIN3B))

Autre désignation: SIN3B

Sujet:

Synonyms: SIN3B, KIAA0700, Paired amphipathic helix protein Sin3b, Histone deacetylase complex subunit Sin3b, Transcriptional corepressor Sin3b

Background: function:Acts as a transcriptional repressor. Interacts with MXI1 to repress MYC responsive genes and antagonize MYC oncogenic activities. Interacts with MAD-MAX heterodimers by binding to MAD. The heterodimer then represses transcription by tethering SIN3B to DNA. Also forms a complex with FOXK1 which represses transcription.,similarity:Contains 3 PAH (paired amphipathic helix) repeats.,subunit:Interacts with FOXK1/MNF, MXI, MAD, NCOR1 and SAP30. Interaction with SDS3 enhances the interaction with HDAC1 to form a complex. Interacts with MAD3, MAD4, MAEL, REST and SETDB1 (By similarity). Interacts with HCFC1.,

Gene Name: SIN3B

Protein Name: Paired amphipathic helix protein Sin3b

Poids moléculaire: 133 kDa

ID gène: 23309

OMIM: 607777

UniProt: O75182