MDS1 anticorps (AA 1-50)
Aperçu rapide pour MDS1 anticorps (AA 1-50) (ABIN1450839)
Antigène
Reactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 1-50
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Fonction
- PRDM3 Antibody
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Specificité
- PRDM3 Polyclonal Antibody detects endogenous levels of PRDM3 protein.
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Purification
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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Immunogène
- The antiserum was produced against synthesized peptide derived from human MECOM. AA range:1-50
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Isotype
- IgG
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Indications d'application
- WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:20000.. IF 1:50-200
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Store at -20°C/1 year
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Date de péremption
- 12 months
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- MDS1 (Myelodysplasia Syndrome 1 (MDS1))
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Autre désignation
- Myelodysplasia Syndrome 1
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Sujet
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Synonyms: MECOM, MDS1, MDS1 and EVI1 complex locus protein MDS1, Myelodysplasia syndrome 1 protein, Myelodysplasia syndrome-associated protein 1
Background: The protein encoded by this gene is a transcriptional regulator and oncoprotein that may be involved in hematopoiesis, apoptosis, development, and cell differentiation and proliferation. The encoded protein can interact with CTBP1, SMAD3, CREBBP, KAT2B, MAPK8, and MAPK9. This gene can undergo translocation with the AML1 gene, resulting in overexpression of this gene and the onset of leukemia. Several transcript variants encoding a few different isoforms have been found for this gene. [provided by RefSeq, Mar 2011],
Gene Name: MECOM
Protein Name: MDS1 and EVI1 complex locus protein MDS1
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Poids moléculaire
- 18 kDa
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ID gène
- 4197
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OMIM
- 600049
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UniProt
- Q13465
Antigène
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