RASD2 anticorps (AA 217-266)

N° du produit ABIN1450860

Cet anticorps anti-RASD2 Polyclonal Lapin (ABIN1450860) détecte spécifiquement RASD2 dans WB et ELISA. L’anticorps est réactif avec des échantillons de Humain, Souris et Rat.

Aperçu rapide pour RASD2 anticorps (AA 217-266) (ABIN1450860)

Antigène: RASD2 (RASD Family, Member 2 (RASD2))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RASD2 est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-RASD2 anticorps

Épitope: AA 217-266

Fonction: Dexras2 Antibody

Specificité: Dexras2 Polyclonal Antibody detects endogenous levels of Dexras2 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: The antiserum was produced against synthesized peptide derived from human RASD2. AA range:217-266

Isotype: IgG

Information d'application

Indications d'application: WB 1:500 - 1:2000. ELISA: 1:40000. Not yet tested in other applications.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C/1 year

Date de péremption: 12 months

Détails sur RASD2

Antigène: RASD2 (RASD Family, Member 2 (RASD2))

Autre désignation: RASD2

Sujet:

Synonyms: RASD2, TEM2, GTP-binding protein Rhes, Ras homolog enriched in striatum, Tumor endothelial marker 2

Background: This gene belongs to the Ras superfamily of small GTPases and is enriched in the striatum. The encoded protein functions as an E3 ligase for attachment of small ubiquitin-like modifier (SUMO). This protein also binds to mutant huntingtin (mHtt), the protein mutated in Huntington disease (HD). Sumoylation of mHTT by this protein may cause degeneration of the striatum. The protein functions as an activator of mechanistic target of rapamycin 1 (mTOR1), which in turn plays a role in myelination, axon growth and regeneration. Reduced levels of mRNA expressed by this gene were found in HD patients. [provided by RefSeq, Jan 2016],

Gene Name: RASD2

Protein Name: GTP-binding protein Rhes

Poids moléculaire: 30 kDa

ID gène: 23551

UniProt: Q96D21