TSG101 anticorps (AA 281-330)

N° du produit ABIN1450872

Cet anticorps anti-TSG101 Polyclonal Lapin (ABIN1450872) détecte spécifiquement TSG101 dans WB, IHC, ELISA et IF. L’anticorps est réactif avec des échantillons de Humain, Souris, Rat et Singe.

Aperçu rapide pour TSG101 anticorps (AA 281-330) (ABIN1450872)

Antigène: TSG101 (Tumor Susceptibility Gene 101 (TSG101))

Reactivité: Humain, Souris, Rat, Singe

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TSG101 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Détail du produit anti-TSG101 anticorps

Épitope: AA 281-330

Fonction: Tsg 101 Antibody

Specificité: Tsg 101 Polyclonal Antibody detects endogenous levels of Tsg 101 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: The antiserum was produced against synthesized peptide derived from human TSG101. AA range:281-330

Isotype: IgG

Information d'application

Indications d'application: WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:5000. Not yet tested in other applications.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C/1 year

Date de péremption: 12 months

Détails sur TSG101

Antigène: TSG101 (Tumor Susceptibility Gene 101 (TSG101))

Autre désignation: TS101

Sujet:

Synonyms: TSG101, Tumor susceptibility gene 101 protein, ESCRT-I complex subunit TSG101

Background: The protein encoded by this gene belongs to a group of apparently inactive homologs of ubiquitin-conjugating enzymes. The gene product contains a coiled-coil domain that interacts with stathmin, a cytosolic phosphoprotein implicated in tumorigenesis. The protein may play a role in cell growth and differentiation and act as a negative growth regulator. In vitro steady-state expression of this tumor susceptibility gene appears to be important for maintenance of genomic stability and cell cycle regulation. Mutations and alternative splicing in this gene occur in high frequency in breast cancer and suggest that defects occur during breast cancer tumorigenesis and/or progression. [provided by RefSeq, Jul 2008],

Gene Name: TSG101

Protein Name: Tumor susceptibility gene 101 protein

Poids moléculaire: 43 kDa

ID gène: 7251

OMIM: 601387

UniProt: Q99816