SLC22A5 anticorps (AA 300-349)
Aperçu rapide pour SLC22A5 anticorps (AA 300-349) (ABIN1451421)
Antigène
Voir toutes SLC22A5 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 300-349
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Fonction
- OCTN2 Antibody
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Specificité
- OCTN2 Polyclonal Antibody detects endogenous levels of OCTN2 protein.
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Purification
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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Immunogène
- The antiserum was produced against synthesized peptide derived from human SLC22A5. AA range:300-349
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Isotype
- IgG
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Indications d'application
- WB 1:500 - 1:2000. ELISA: 1:20000. Not yet tested in other applications.
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Store at -20°C/1 year
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Date de péremption
- 12 months
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- SLC22A5 (Solute Carrier Family 22 Member 5 (SLC22A5))
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Autre désignation
- SLC22A5
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Sujet
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Synonyms: SLC22A5, OCTN2, Solute carrier family 22 member 5, High-affinity sodium-dependent carnitine cotransporter, Organic cation/carnitine transporter 2
Background: Polyspecific organic cation transporters in the liver, kidney, intestine, and other organs are critical for elimination of many endogenous small organic cations as well as a wide array of drugs and environmental toxins. The encoded protein is a plasma integral membrane protein which functions both as an organic cation transporter and as a sodium-dependent high affinity carnitine transporter. The encoded protein is involved in the active cellular uptake of carnitine. Mutations in this gene are the cause of systemic primary carnitine deficiency (CDSP), an autosomal recessive disorder manifested early in life by hypoketotic hypoglycemia and acute metabolic decompensation, and later in life by skeletal myopathy or cardiomyopathy. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Apr 2015],
Gene Name: SLC22A5
Protein Name: Solute carrier family 22 member 5
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Poids moléculaire
- 62 kDa
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ID gène
- 6584
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OMIM
- 212140
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UniProt
- O76082
Antigène
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