EWSR1 anticorps (AA 403-452)

N° du produit ABIN1451580

Cet anticorps anti-EWSR1 Polyclonal Lapin (ABIN1451580) détecte spécifiquement EWSR1 dans WB et ELISA. L’anticorps est réactif avec des échantillons de Humain, Souris et Rat.

Aperçu rapide pour EWSR1 anticorps (AA 403-452) (ABIN1451580)

Antigène: EWSR1 (Ewing Sarcoma Breakpoint Region 1 (EWSR1))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp EWSR1 est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-EWSR1 anticorps

Épitope: AA 403-452

Fonction: EWS Antibody

Specificité: EWS Polyclonal Antibody detects endogenous levels of EWS protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: The antiserum was produced against synthesized peptide derived from human EWSR1. AA range:403-452

Isotype: IgG

Information d'application

Indications d'application: WB 1:500 - 1:2000. ELISA: 1:10000. Not yet tested in other applications.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C/1 year

Date de péremption: 12 months

Détails sur EWSR1

Antigène: EWSR1 (Ewing Sarcoma Breakpoint Region 1 (EWSR1))

Autre désignation: EWSR1

Sujet:

Synonyms: EWSR1, EWS, RNA-binding protein EWS, EWS oncogene, Ewing sarcoma breakpoint region 1 protein

Background: This gene encodes a multifunctional protein that is involved in various cellular processes, including gene expression, cell signaling, and RNA processing and transport. The protein includes an N-terminal transcriptional activation domain and a C-terminal RNA-binding domain. Chromosomal translocations between this gene and various genes encoding transcription factors result in the production of chimeric proteins that are involved in tumorigenesis. These chimeric proteins usually consist of the N-terminal transcriptional activation domain of this protein fused to the C-terminal DNA-binding domain of the transcription factor protein. Mutations in this gene, specifically a t(11,22)(q24,q12) translocation, are known to cause Ewing sarcoma as well as neuroectodermal and various other tumors. Alternative splicing of this gene results in multiple transcript variants. Related pseudogenes have been id

Gene Name: EWSR1

Protein Name: RNA-binding protein EWS

Poids moléculaire: 68 kDa

ID gène: 2130

OMIM: 133450

UniProt: Q01844