ANAPC5 anticorps (AA 151-200)

N° du produit ABIN1452003

Cet anticorps anti-ANAPC5 Polyclonal Lapin (ABIN1452003) détecte spécifiquement ANAPC5 dans WB et ELISA. L’anticorps est réactif avec des échantillons de Humain, Souris et Rat.

Aperçu rapide pour ANAPC5 anticorps (AA 151-200) (ABIN1452003)

Antigène: ANAPC5 (Anaphase Promoting Complex Subunit 5 (ANAPC5))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ANAPC5 est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-ANAPC5 anticorps

Épitope: AA 151-200

Fonction: APC5 Antibody

Specificité: APC5 Polyclonal Antibody detects endogenous levels of APC5 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: The antiserum was produced against synthesized peptide derived from human ANAPC5. AA range:151-200

Isotype: IgG

Information d'application

Indications d'application: WB 1:500 - 1:2000. ELISA: 1:5000. Not yet tested in other applications.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C/1 year

Date de péremption: 12 months

Détails sur ANAPC5

Antigène: ANAPC5 (Anaphase Promoting Complex Subunit 5 (ANAPC5))

Autre désignation: ANAPC5

Sujet:

Synonyms: ANAPC5, APC5, Anaphase-promoting complex subunit 5, APC5, Cyclosome subunit 5

Background: This gene encodes a tetratricopeptide repeat-containing component of the anaphase promoting complex/cyclosome (APC/C), a large E3 ubiquitin ligase that controls cell cycle progression by targeting a number of cell cycle regulators such as B-type cyclins for 26S proteasome-mediated degradation through ubiquitination. The encoded protein is required for the proper ubiquitination function of APC/C and for the interaction of APC/C with transcription coactivators. It also interacts with polyA binding protein and represses internal ribosome entry site-mediated translation. Multiple transcript variants encoding different isoforms have been found for this gene. These differences cause translation initiation at a downstream AUG and result in a shorter protein (isoform b), compared to isoform a. [provided by RefSeq, Nov 2008],

Gene Name: ANAPC5

Protein Name: Anaphase-promoting complex subunit 5

Poids moléculaire: 85 kDa

ID gène: 51433

OMIM: 606948

UniProt: Q9UJX4

Pathways: M Phase