Desmoglein 1 anticorps (AA 161-210)

N° du produit ABIN1452168

Cet anticorps anti-Desmoglein 1 Polyclonal Lapin (ABIN1452168) détecte spécifiquement Desmoglein 1 dans WB et ELISA. L’anticorps est réactif avec des échantillons de Humain et Souris.

Aperçu rapide pour Desmoglein 1 anticorps (AA 161-210) (ABIN1452168)

Antigène: Desmoglein 1 (DSG1)

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Desmoglein 1 est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-Desmoglein 1 anticorps

Épitope: AA 161-210

Fonction: Dsg1 Antibody

Specificité: Dsg1 Polyclonal Antibody detects endogenous levels of Dsg1 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: The antiserum was produced against synthesized peptide derived from human DSG1. AA range:161-210

Isotype: IgG

Information d'application

Indications d'application: WB 1:500 - 1:2000. ELISA: 1:40000. Not yet tested in other applications.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C/1 year

Date de péremption: 12 months

Détails sur Desmoglein 1

Antigène: Desmoglein 1 (DSG1)

Autre désignation: DSG1

Sujet:

Synonyms: DSG1, CDHF4, Desmoglein-1, Cadherin family member 4, Desmosomal glycoprotein 1, DG1, DGI, Pemphigus foliaceus antigen

Background: This gene encodes a member of the desmoglein protein subfamily. Desmogleins, along with desmocollins, are cadherin-like transmembrane glycoproteins that are major components of the desmosome. Desmosomes are cell-cell junctions that help resist shearing forces and are found in high concentrations in cells subject to mechanical stress. This gene is found in a cluster with other desmoglein family members on chromosome 18. The encoded protein has been identified as a target of auto-antibodies in the autoimmune skin blistering disease pemphigus foliaceus. Disruption of this gene has also been associated with the skin diseases palmoplantar keratoderma and erythroderma. [provided by RefSeq, Feb 2015],

Gene Name: DSG1

Protein Name: Desmoglein-1

Poids moléculaire: 113 kDa

ID gène: 1828

OMIM: 125670

UniProt: Q02413

Pathways: Cell-Cell Junction Organization