ITIH2 anticorps (Cleaved-Asp702)
Aperçu rapide pour ITIH2 anticorps (Cleaved-Asp702) (ABIN1452255)
Antigène
Voir toutes ITIH2 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 653-702, Cleaved-Asp702
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Fonction
- Cleaved-ITI-H2 (D702) Antibody
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Specificité
- Cleaved-ITI-H2 (D702) Polyclonal Antibody detects endogenous levels of fragment of activated ITI-H2 protein resulting from cleavage adjacent to D702.
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Purification
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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Immunogène
- The antiserum was produced against synthesized peptide derived from human ITIH2. AA range:653-702
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Isotype
- IgG
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Indications d'application
- WB 1:500 - 1:2000. ELISA: 1:10000. Not yet tested in other applications.
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Store at -20°C/1 year
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Date de péremption
- 12 months
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- ITIH2 (Inter-alpha Globulin Inhibitor H2 Polypeptide (ITIH2))
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Autre désignation
- ITIH2
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Sujet
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Synonyms: ITIH2, IGHEP2, Inter-alpha-trypsin inhibitor heavy chain H2, ITI heavy chain H2, ITI-HC2, Inter-alpha-inhibitor heavy chain 2, Inter-alpha-trypsin inhibitor complex component II, Serum-derived hyaluronan-associated protein, SHAP
Background: The inter-alpha-trypsin inhibitors (ITI) are a family of structurally related plasma serine protease inhibitors involved in extracellular matrix stabilization and in prevention of tumor metastasis. The ITI family contains multiple proteins made up of a light chain (see MIM 176870) and a variable number of heavy chains (Salier et al., 1987 [PubMed 2446322], Himmelfarb et al., 2004 [PubMed 14744536]).[supplied by OMIM, Nov 2009],
Gene Name: ITIH2
Protein Name: Inter-alpha-trypsin inhibitor heavy chain H2
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Poids moléculaire
- 106 kDa
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ID gène
- 3698
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OMIM
- 146640
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UniProt
- P19823
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Pathways
- Glycosaminoglycan Metabolic Process
Antigène
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