GJB2 anticorps (AA 45-94)

N° du produit ABIN1453152

Cet anticorps anti-GJB2 Polyclonal Lapin (ABIN1453152) détecte spécifiquement GJB2 dans WB et ELISA. L’anticorps est réactif avec des échantillons de Humain, Souris et Rat.

Aperçu rapide pour GJB2 anticorps (AA 45-94) (ABIN1453152)

Antigène: GJB2 (Gap Junction Protein, beta 2, 26kDa (GJB2))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GJB2 est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-GJB2 anticorps

Épitope: AA 45-94

Fonction: Connexin-26 Antibody

Specificité: Connexin-26 Polyclonal Antibody detects endogenous levels of Connexin-26 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: The antiserum was produced against synthesized peptide derived from human Connexin-26. AA range:45-94

Isotype: IgG

Information d'application

Indications d'application: WB 1:500 - 1:2000. ELISA: 1:5000. Not yet tested in other applications.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C/1 year

Date de péremption: 12 months

Détails sur GJB2

Antigène: GJB2 (Gap Junction Protein, beta 2, 26kDa (GJB2))

Autre désignation: Connexin-26

Sujet:

Synonyms: GJB2, Gap junction beta-2 protein, Connexin-26, Cx26

Background: This gene encodes a member of the gap junction protein family. The gap junctions were first characterized by electron microscopy as regionally specialized structures on plasma membranes of contacting adherent cells. These structures were shown to consist of cell-to-cell channels that facilitate the transfer of ions and small molecules between cells. The gap junction proteins, also known as connexins, purified from fractions of enriched gap junctions from different tissues differ. According to sequence similarities at the nucleotide and amino acid levels, the gap junction proteins are divided into two categories, alpha and beta. Mutations in this gene are responsible for as much as 50 % of pre-lingual, recessive deafness. [provided by RefSeq, Oct 2008],

Gene Name: GJB2

Protein Name: Gap junction beta-2 protein

Poids moléculaire: 26 kDa

ID gène: 2706

OMIM: 121011

UniProt: P29033

Pathways: Sensory Perception of Sound, Cell-Cell Junction Organization