alpha Defensin 1 anticorps (AA 3-52)
Aperçu rapide pour alpha Defensin 1 anticorps (AA 3-52) (ABIN1453194)
Antigène
Voir toutes alpha Defensin 1 (DEFA1) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
-
-
Épitope
- AA 3-52
-
Fonction
- Defensin α1 Antibody
-
Specificité
- Defensin α1 Polyclonal Antibody detects endogenous levels of Defensin α1 protein.
-
Purification
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
-
Immunogène
- The antiserum was produced against synthesized peptide derived from human Defensin alpha1. AA range:3-52
-
Isotype
- IgG
-
-
-
-
Indications d'application
- IHC 1:100 - 1:300. ELISA: 1:40000.. IF 1:50-200
-
Restrictions
- For Research Use only
-
-
-
Format
- Liquid
-
Concentration
- 1 mg/mL
-
Buffer
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
-
Agent conservateur
- Sodium azide
-
Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Stock
- -20 °C
-
Stockage commentaire
- Store at -20°C/1 year
-
Date de péremption
- 12 months
-
-
- alpha Defensin 1 (DEFA1) (Defensin, alpha 1 (DEFA1))
-
Autre désignation
- Defensin Alpha1
-
Sujet
-
Synonyms: DEFA1, DEF1, DEFA2, MRS, DEFA1B, Neutrophil defensin 1, Defensin, alpha 1, HNP-1, HP-1, HP1
Background: defensin alpha 1(DEFA1) Homo sapiens Defensins are a family of antimicrobial and cytotoxic peptides thought to be involved in host defense. They are abundant in the granules of neutrophils and also found in the epithelia of mucosal surfaces such as those of the intestine, respiratory tract, urinary tract, and vagina. Members of the defensin family are highly similar in protein sequence and distinguished by a conserved cysteine motif.The protein encoded by this gene, defensin, alpha 1, is found in the microbicidal granules of neutrophils and likely plays a role in phagocyte-mediated host defense. Several alpha defensin genes are clustered on chromosome 8. This gene differs from defensin, alpha 3 by only one amino acid. This gene and the gene encoding defensin, alpha 3 are both subject to copy number variation. [provided by RefSeq, Oct 2014],
Gene Name: DEFA1
Protein Name: Neutrophil defensin 1
-
Poids moléculaire
- 10 kDa
-
ID gène
- 1667
-
OMIM
- 125220
-
UniProt
- P59665
-
Pathways
- Cellular Response to Molecule of Bacterial Origin
Antigène
-