EEA1 anticorps (AA 205-254)

N° du produit ABIN1453230

Cet anticorps anti-EEA1 Polyclonal Lapin (ABIN1453230) détecte spécifiquement EEA1 dans WB et ELISA. L’anticorps est réactif avec des échantillons de Humain et Souris.

Aperçu rapide pour EEA1 anticorps (AA 205-254) (ABIN1453230)

Antigène: EEA1 (Early Endosome Antigen 1 (EEA1))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp EEA1 est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-EEA1 anticorps

Épitope: AA 205-254

Fonction: EEA1 Antibody

Specificité: EEA1 Polyclonal Antibody detects endogenous levels of EEA1 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: The antiserum was produced against synthesized peptide derived from human EEA1. AA range:205-254

Isotype: IgG

Information d'application

Indications d'application: WB 1:500 - 1:2000. ELISA: 1:20000. Not yet tested in other applications.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C/1 year

Date de péremption: 12 months

Détails sur EEA1

Antigène: EEA1 (Early Endosome Antigen 1 (EEA1))

Autre désignation: EEA1

Sujet:

Synonyms: EEA1, ZFYVE2, Early endosome antigen 1, Endosome-associated protein p162, Zinc finger FYVE domain-containing protein 2

Background: disease:Antibodies against EEA1 are found in sera from patients with subacute cutaneous lupus erythematosus and other autoimmune diseases.,domain:The FYVE-type zinc finger domain mediates interactions with phosphatidylinositol 3-phosphate.,function:Binds phospholipid vesicles containing phosphatidylinositol 3-phosphate and participates in endosomal trafficking.,similarity:Contains 1 C2H2-type zinc finger.,similarity:Contains 1 FYVE-type zinc finger.,subunit:Homodimer. Binds STX6. Binds RAB5A, RAB5B, RAB5C and RAB22A that have been activated by GTP-binding.,

Gene Name: EEA1

Protein Name: Early endosome antigen 1

Poids moléculaire: 162 kDa

ID gène: 8411

OMIM: 605070

UniProt: Q15075

Pathways: Toll-Like Receptors Cascades