NQO1 anticorps (AA 203-252)

N° du produit ABIN1453680

Cet anticorps anti-NQO1 Polyclonal Lapin (ABIN1453680) détecte spécifiquement NQO1 dans WB, ELISA et IF. L’anticorps est réactif avec des échantillons de Humain, Souris et Rat.

Aperçu rapide pour NQO1 anticorps (AA 203-252) (ABIN1453680)

Antigène: NQO1 (NAD(P)H Dehydrogenase, Quinone 1 (NQO1))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp NQO1 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF)

Détail du produit anti-NQO1 anticorps

Épitope: AA 203-252

Fonction: NQO1 Antibody

Specificité: NQO1 Polyclonal Antibody detects endogenous levels of NQO1 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: The antiserum was produced against synthesized peptide derived from human NQO1. AA range:203-252

Isotype: IgG

Information d'application

Indications d'application: WB 1:500 - 1:2000. IF 1:50-200 ELISA: 1:10000. Not yet tested in other applications.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C/1 year

Date de péremption: 12 months

Détails sur NQO1

Antigène: NQO1 (NAD(P)H Dehydrogenase, Quinone 1 (NQO1))

Autre désignation: NQO1

Sujet:

Synonyms: NQO1; DIA4; NMOR1; NAD(P)H dehydrogenase [quinone] 1; Azoreductase; DT-diaphorase; DTD; Menadione reductase; NAD(P)H:quinone oxidoreductase 1; Phylloquinone reductase; Quinone reductase 1; QR1

Background: This gene is a member of the NAD(P)H dehydrogenase (quinone) family and encodes a cytoplasmic 2-electron reductase. This FAD-binding protein forms homodimers and reduces quinones to hydroquinones. This protein's enzymatic activity prevents the one electron reduction of quinones that results in the production of radical species. Mutations in this gene have been associated with tardive dyskinesia (TD), an increased risk of hematotoxicity after exposure to benzene, and susceptibility to various forms of cancer. Altered expression of this protein has been seen in many tumors and is also associated with Alzheimer's disease (AD). Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008],

Gene Name: NQO1

Protein Name: NAD(P)H dehydrogenase [quinone] 1

Poids moléculaire: 30 kDa

ID gène: 1728

OMIM: 125860

UniProt: P15559