Peroxiredoxin 3 anticorps (AA 44-93)
Aperçu rapide pour Peroxiredoxin 3 anticorps (AA 44-93) (ABIN1453824)
Antigène
Voir toutes Peroxiredoxin 3 (PRDX3) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 44-93
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Fonction
- PRX III Antibody
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Specificité
- PRX III Polyclonal Antibody detects endogenous levels of PRX III protein.
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Purification
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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Immunogène
- The antiserum was produced against synthesized peptide derived from human PRX III. AA range:44-93
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Isotype
- IgG
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Indications d'application
- WB 1:500 - 1:2000.IHC:1:50-300 IP 1:50-200 ELISA: 1:20000.. IF 1:50-200
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Store at -20°C/1 year
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Date de péremption
- 12 months
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- Peroxiredoxin 3 (PRDX3)
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Autre désignation
- PRX III
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Sujet
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Synonyms: PRDX3, AOP1, Thioredoxin-dependent peroxide reductase, mitochondrial, Antioxidant protein 1, AOP-1, HBC189, Peroxiredoxin III, Prx-III, Peroxiredoxin-3, Protein MER5 homolog
Background: This gene encodes a mitochondrial protein with antioxidant function. The protein is similar to the C22 subunit of Salmonella typhimurium alkylhydroperoxide reductase, and it can rescue bacterial resistance to alkylhydroperoxide in E. coli that lack the C22 subunit. The human and mouse genes are highly conserved, and they map to the regions syntenic between mouse and human chromosomes. Sequence comparisons with recently cloned mammalian homologs suggest that these genes consist of a family that is responsible for the regulation of cellular proliferation, differentiation and antioxidant functions. This family member can protect cells from oxidative stress, and it can promote cell survival in prostate cancer. Alternative splicing of this gene results in multiple transcript variants. Related pseudogenes have been identified on chromosomes 1, 3, 13 and 22. [provided by RefSeq, Oct 2014],
Gene Name: PRDX3
Protein Name: Thioredoxin-dependent peroxide reductase mitochondrial
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Poids moléculaire
- 27 kDa
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ID gène
- 10935
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OMIM
- 604769
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UniProt
- P30048
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Pathways
- Ribonucleoside Biosynthetic Process, Methionine Biosynthetic Process
Antigène
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