LTA anticorps (AA 17-66)
Aperçu rapide pour LTA anticorps (AA 17-66) (ABIN1454001)
Antigène
Voir toutes LTA AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
-
-
Épitope
- AA 17-66
-
Fonction
- TNF-β Antibody
-
Specificité
- TNF-β Polyclonal Antibody detects endogenous levels of TNF-β protein.
-
Purification
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
-
Immunogène
- The antiserum was produced against synthesized peptide derived from human TNF-beta. AA range:17-66
-
Isotype
- IgG
-
-
-
-
Indications d'application
- WB 1:500 - 1:2000. ELISA: 1:40000. Not yet tested in other applications.
-
Restrictions
- For Research Use only
-
-
-
Format
- Liquid
-
Concentration
- 1 mg/mL
-
Buffer
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
-
Agent conservateur
- Sodium azide
-
Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Stock
- -20 °C
-
Stockage commentaire
- Store at -20°C/1 year
-
Date de péremption
- 12 months
-
-
- LTA (Lymphotoxin-alpha (LTA))
-
Autre désignation
- TNF-beta
-
Classe de substances
- Chemical
-
Sujet
-
Synonyms: LTA; TNFB; TNFSF1; Lymphotoxin-alpha; LT-alpha; TNF-beta; Tumor necrosis factor ligand superfamily member 1
Background: The encoded protein, a member of the tumor necrosis factor family, is a cytokine produced by lymphocytes. The protein is highly inducible, secreted, and forms heterotrimers with lymphotoxin-beta which anchor lymphotoxin-alpha to the cell surface. This protein also mediates a large variety of inflammatory, immunostimulatory, and antiviral responses, is involved in the formation of secondary lymphoid organs during development and plays a role in apoptosis. Genetic variations in this gene are associated with susceptibility to leprosy type 4, myocardial infarction, non-Hodgkin's lymphoma, and psoriatic arthritis. Alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq, Jul 2012],
Gene Name: LTA
Protein Name: Lymphotoxin-alpha
-
Poids moléculaire
- 22 kDa
-
ID gène
- 4049
-
OMIM
- 153440
-
UniProt
- P01374
-
Pathways
- Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process
Antigène
-