TTF1 anticorps (AA 27-76)

N° du produit ABIN1454046

Cet anticorps anti-TTF1 Polyclonal Lapin (ABIN1454046) détecte spécifiquement TTF1 dans WB et ELISA. L’anticorps est réactif avec des échantillons de Humain, Rat et Souris.

Aperçu rapide pour TTF1 anticorps (AA 27-76) (ABIN1454046)

Antigène: TTF1 (Transcription Termination Factor, RNA Polymerase I (TTF1))

Reactivité: Humain, Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TTF1 est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-TTF1 anticorps

Épitope: AA 27-76

Fonction: TTF-1 Antibody

Specificité: TTF-1 Polyclonal Antibody detects endogenous levels of TTF-1 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: The antiserum was produced against synthesized peptide derived from human TTF-1. AA range:27-76

Isotype: IgG

Information d'application

Indications d'application: WB 1:500 - 1:2000. ELISA: 1:10000. Not yet tested in other applications.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C/1 year

Date de péremption: 12 months

Détails sur TTF1

Antigène: TTF1 (Transcription Termination Factor, RNA Polymerase I (TTF1))

Autre désignation: TTF-1

Sujet:

Synonyms: NKX2-1; NKX2A; TITF1; TTF1; Homeobox protein Nkx-2.1; Homeobox protein NK-2 homolog A; Thyroid nuclear factor 1; Thyroid transcription factor 1; TTF-1

Background: This gene encodes a protein initially identified as a thyroid-specific transcription factor. The encoded protein binds to the thyroglobulin promoter and regulates the expression of thyroid-specific genes but has also been shown to regulate the expression of genes involved in morphogenesis. Mutations and deletions in this gene are associated with benign hereditary chorea, choreoathetosis, congenital hypothyroidism, and neonatal respiratory distress, and may be associated with thyroid cancer. Multiple transcript variants encoding different isoforms have been found for this gene. This gene shares the symbol/alias 'TTF1' with another gene, transcription termination factor 1, which plays a role in ribosomal gene transcription. [provided by RefSeq, Feb 2014],

Gene Name: NKX2-1

Protein Name: Homeobox protein Nkx-2.1

Poids moléculaire: 38 kDa

ID gène: 7080

OMIM: 600635

UniProt: P43699

Pathways: Thyroid Hormone Synthesis, Regulation of Systemic Arterial Blood Pressure by Hormones, Feeding Behaviour