UCP3 anticorps (AA 259-308)

N° du produit ABIN1454058

Cet anticorps anti-UCP3 Polyclonal Lapin (ABIN1454058) détecte spécifiquement UCP3 dans WB et ELISA. L’anticorps est réactif avec des échantillons de Humain, Souris et Rat.

Aperçu rapide pour UCP3 anticorps (AA 259-308) (ABIN1454058)

Antigène: UCP3 (Uncoupling Protein 3 (Mitochondrial, Proton Carrier) (UCP3))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp UCP3 est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-UCP3 anticorps

Épitope: AA 259-308

Fonction: UCP3 Antibody

Specificité: UCP3 Polyclonal Antibody detects endogenous levels of UCP3 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: The antiserum was produced against synthesized peptide derived from human UCP3. AA range:259-308

Isotype: IgG

Information d'application

Indications d'application: WB 1:500 - 1:2000. ELISA: 1:10000. Not yet tested in other applications.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C/1 year

Date de péremption: 12 months

Détails sur UCP3

Antigène: UCP3 (Uncoupling Protein 3 (Mitochondrial, Proton Carrier) (UCP3))

Autre désignation: UCP3

Sujet:

Synonyms: UCP3; SLC25A9; Mitochondrial uncoupling protein 3; UCP 3; Solute carrier family 25 member 9

Background: Mitochondrial uncoupling proteins (UCP) are members of the larger family of mitochondrial anion carrier proteins (MACP). UCPs separate oxidative phosphorylation from ATP synthesis with energy dissipated as heat, also referred to as the mitochondrial proton leak. UCPs facilitate the transfer of anions from the inner to the outer mitochondrial membrane and the return transfer of protons from the outer to the inner mitochondrial membrane. They also reduce the mitochondrial membrane potential in mammalian cells. The different UCPs have tissue-specific expression; this gene is primarily expressed in skeletal muscle. This gene's protein product is postulated to protect mitochondria against lipid-induced oxidative stress. Expression levels of this gene increase when fatty acid supplies to mitochondria exceed their oxidation capacity and the protein enables the export of fatty acids from mitochondria.

Gene Name: UCP3

Protein Name: Mitochondrial uncoupling protein 3

Poids moléculaire: 34 kDa

ID gène: 7352

OMIM: 602044

UniProt: P55916

Pathways: Proton Transport