anticorps Chc1, anticorps zgc:65796, anticorps zgc:77114, anticorps wu:fj77f08, anticorps rcc1, anticorps chc1-a, anticorps BJ1, anticorps CG10480, anticorps CG18640 (Bj1), anticorps Dmel\\CG10480, anticorps RCC1, anticorps RanGEF, anticorps Rcc1, anticorps dRCC1, anticorps inxs, anticorps sdt, anticorps xrcc1, anticorps chc1-b, anticorps MGC115703, anticorps MGC132085, anticorps CHC1, anticorps RCC1-I, anticorps SNHG3-RCC1, anticorps 4931417M11Rik, anticorps AI326872, anticorps regulator of chromosome condensation 1, anticorps regulator of chromosome condensation 1 L homeolog, anticorps Regulator of chromosome condensation 1, anticorps N terminal fragment of RCC1; similar to S. cerevisiae SRM1 (YGL097W) guanine nucleotide exchange factor for Gsp1 GTPase involved in assembly of nuclear pore complex; frameshifted, anticorps regulator of chromosome condensation 1 S homeolog, anticorps rcc1, anticorps RCC1, anticorps rcc1.L, anticorps Rcc1, anticorps rcc1.S
Sujet
Guanine-nucleotide releasing factor that promotes the exchange of Ran-bound GDP by GTP, and thereby plays an important role in RAN-mediated functions in nuclear import and mitosis. Contributes to the generation of high levels of chromosome-associated, GTP-bound RAN, which is important for mitotic spindle assembly and normal progress through mitosis. Via its role in maintaining high levels of GTP-bound RAN in the nucleus, contributes to the release of cargo proteins from importins after nuclear import. Involved in the regulation of onset of chromosome condensation in the S phase. Binds both to the nucleosomes and double-stranded DNA.,CHC1, RCC1-I, SNHG3-RCC1,Cell Biology & Developmental Biology,Cell Cycle,RCC1